Bone Marrow Transplant Treatment

What is Bone Marrow Transplant?

Bone marrow is a spongy tissue in the hollow centres of a person's long bones. These immature cells further gets mature into red blood cells, white blood cells and platelets. 
Red blood cell's role is to carry oxygen and nutrients throughout the body. Platelets helps in control bleeding by forming clots.  
Stem cells constantly gets divided and produce new cells. Stem cells rapidly get multiplied to make millions of blood cells each day. Blood cells have a limited life span 
(around 100-120 days for red blood cells) and gets constantly being replaced. The production of healthy stem cells is important. Healthy bone marrow release blood cells into 
the bloodstream when they are mature and whenever required. Without the help of bone marrow, our bodies could not produce the white cells we need to fight infection, the red blood 
cells we need to carry oxygen, and the platelets we need to stop bleeding. Some illnesses as well as treatments can destroy the bone marrow. This leaves the person unable to make 
the new blood cells which are needed to fight infection and recover. In some cases, the best treatment is a transplant of bone marrow donated by other person.

Why is a bone marrow transplant needed?

They are performed when a person's marrow gets destroyed by a disease or isn't healthy enough to function properly.
A bone marrow transplant can be used to:

• Replace diseased, non-functioning bone marrow with healthy and functioning bone marrow for conditions such as leukemia, aplastic anemia, and sickle cell anemia.
• Regenerate a new immune system that will fight existing or residual leukemia or other cancers not killed by the chemotherapy or radiation that are used in the transplant. 
• Replace the bone marrow and restore its normal function after high doses of chemotherapy and/or radiation are given for treating a malignancy.
• Replace bone marrow with genetically healthy and functioning bone marrow to prevent further damage from a genetic disease process.

What does the operation involve?

In a transplant operation, the person receiving the marrow is treated with a high dose of chemotherapy or radiotherapy to destroy their diseased cells. The donor's bone 
marrow cells are then injected into a vein, just like blood transfusion. The donor marrow finds the bones and settles into the existing cavities. Donating bone marrow can save other 
person's life. Bone marrow donors are matched with the people who need a transplant to survive. The donor must have same tissue type as the recipient. Doctors can check a person's 
tissue type with a simple blood test.

Also read :- Best Cancer Hospitals in India

What complications can happen during bone marrow transplant treatment in India 

There are a number of diseases that affect the bone marrow including, Leukaemia - a cancer of the blood that starts in the bone marrow. We don't know its exact cause. Symptoms 
include anaemia, bruising as well as nose bleeds. Treatment includes chemotherapy and radiotherapy, and sometimes a bone marrow transplant from a healthy compatible person. 
Reticulum cell sarcoma of bone - a cancerous tumour of bone marrow, occurring more often in males than in females. Symptoms include pain and swelling. Can be treated by 
radiotherapy. Aplastic anaemia-a person stops making blood. This happens mostly in people between 15 and 30 age. The person may have the condition at birth, or certain drugs, 
chemicals and radiation may be the cause, often the cause is unknown. Symptoms include weakness, fever and skin haemorrhages. Blood transfusions may help for a time, but a 
severely affected person may die, unless they receive a transplant of healthy bone marrow. Defective immune system - some children are born with a defective immune system and are 
unable to fight the disease. Blood transfusions can help, but in most serious cases, the person will only respond to a bone marrow transplant. During the initial weeks and months 
after leaving the hospital, the patient will have to make frequent trips to an outpatient clinic. This will allow the doctors to track down the patient's progress. These visits will 
become less frequent over time.

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Myths & Facts about Bone Marrow Transplant

• MYTH: All the bone marrow donations involve surgery.
• FACT: Major part of bone marrow donations do not involve surgery. Today, the patient's doctor most often requests a peripheral blood stem cell donation,

Which is a non-surgical procedure.

• MYTH: Donating bone marrow is painful and involve a long recover.
• FACT: Donating bone marrow can have uncomfortable but short-lived side effects. This is because of taking a drug known as filgrastim. Donors may have headaches, joint or muscle 

aches and/or fatigue. Usually the donors are back to their normal routine in one to two days.
 

• MYTH: In marrow donation, pieces of bone are detached from the donor.
• FACT: No pieces of bone are detached during marrow donation. Bone marrow is a fluid within the cavities of bones and contains stem cells which are the source of all blood cells. 

Only this liquid marrow inside the bone is needed to save the patient's life.
 

• MYTH: Most patients receive their marrow from a family member.
• FACT: 70 percent of the patients will receive their marrow from a stranger.
• MYTH: I can't donate my marrow because I can't donate my blood.
• FACT: Requirements for donating blood are very different from donating bone marrow. There is no underweight requirement for bone marrow donations but there is a 

maximum weight requirement. People who are anemic or deficiency of iron can donate and even those with diabetics whose condition is not controlled by insulin can also donate. 
However, if they experience chronic back or hip or spine problems that requires medical attention, or if they have had a disc problem, then they may not be allowed to donate.

Follow-Up

Blood cells are made inside of bone marrow. Diseases of bone marrow affect the production of the blood cells. Some illnesses and treatments require bone marrow transplants. A bone 
marrow transplant involves matching tissue types of the donor and the recipient. It is very hard to find the exact tissue matches outside families. 
India provides cost effective treatments to its patients. The cost of bone marrow transplant in India, therefore is also much lesser than what it is in other countries abroad. Check 
out the links below to know the cost of bone marrow transplant in India thoroughly:  The register is completely confidential.

Bone Marrow Transplant In India 

Blood cells including platelets, leukocytes (WBC), and erythrocytes (RBC) are produced in bone marrow. The body cannot create healthy blood cells from a sick or injured bone marrow, which prevents the body from functioning normally and can result in more serious issues.

Bone Marrow Transplant In Gurgaon 

A bone marrow transplant, sometimes referred to as a stem cell transplant or hematopoietic stem cell transplantation, is a surgical procedure in which diseased or damaged bone marrow is replaced with healthy stem cells. 

Need for Hematopoietic Stem Cell Transplant

When a person's bone marrow isn't working properly, they need a bone marrow transplant. Numerous conditions as well as the side effects of radiation or chemotherapy for cancer, might contribute to this. Bone marrow transplants are an option when all other treatments have failed. 

Bone marrow transplant is a curative treatment for various diseases:

• Thalassemia & Sickle cell disease.
• Aplastic anemia.
• Leukemia (ALL, AML, CML, CLL).
• Multiple myeloma.
• High grade lymphomas.
• Neuroblastoma.
• Wilm’s tumor.
• High grade sarcomas.

Types of Bone marrow transplant

Autologous bone marrow transplant:

The word "auto" refers to "self," meaning that the patient's removed stem cells are stored and reinjected into the body. This method involves removing the patient's own healthy stem cells using a technique known as apheresis. Rescue transplant is another term for the procedure.

Allogeneic Transplant:

During this process, stem cells are harvested from a donor to create bone marrow. A family member or an unrelated third party may be the donor. If the recipient's and donor's bone marrow tissues are compatible, the surgery can proceed.

Umbilical cord transplant: 

This procedure involves taking stem cells right after delivery from the umbilical cord of a newborn. After being gathered, these stem cells are kept for further use. However, this kind of transplant recovery may take longer due to the reduced quantity of stem cells.

Bone marrow transplant for Sickle Cell Anemia: the only treatment for this disease

A genetic blood condition known as sickle cell anemia results in blood cells that are sticky, rigid, and shaped like a sickle, or "C." Consequently, cells may get lodged in the blood vessels during their passage, obstructing the blood's ability to circulate throughout the body. 

BMT is the only treatment that can cure sickle cell disease.However, approximately 20–30% of people who require it have a matching sibling who can give bone marrow on their behalf. 

BMT has been used to treat and cure sickle cell disease in children over the past 20 years. Our BMT team and Sickle Cell team work closely together. Our knowledge of the sickle cell program and the BMT division enables us to help parents make this challenging choice.

Stem cell transplant in India for International Patients

The availability of qualified physicians and advancements in medical technology are the main reasons behind the rise in bone marrow transplants in India. Some of the top bone marrow transplant facilities in India feature state-of-the-art equipment and a group of highly skilled medical professionals committed to giving patients the best care possible. In India, the success rate for bone marrow transplants varies from 60% to 85%. For patients seeking a bone marrow transplant, India is an excellent option because of its inexpensive pricing and good success rates.

Bone marrow biopsy in India: A diagnostic test before undergoing Bone Marrow Transplant

A bone marrow biopsy involves a physician taking a sample of the patient's bone marrow to check the health of the tissue and blood cell production. Anemia, clotting issues, leukemia, multiple myeloma and some cancers can be diagnosed with the use of a bone marrow biopsy. Determining whether a donor is a suitable candidate for an allogeneic stem cell transplant also can be done by a bone marrow biopsy. 

Medical Visa Process

Step 1: Eligibility for Medical Visa

• A medical visa is also known as M visa, which is issued to the foreign patients visiting India for sharing medical treatment.
• Inviting only two persons – relatives or other persons connected with the applicant in any other way – can accompany the applicant on the Medical Attendant Visa (MX visa).
• The patient should be in search of treatment in any accredited hospital in India.

Step 2: Gather Required Documents

You will need:

• Medical documents: A letter from the hospital of India stating that the medical condition of the patient has been treated and they have undergone through liver transplant.
• Client Medical History: Information on the liver disease: diagnosis report, treatment and doctor advice.
• Visa Application Form: Intended visa application form duly completed, which could only be downloaded from the website of Indian embassy in your country.
• Passport: Valid for at least six months with at least two blank pages.
• Necessary number of photos as per the provision of the Indian Visa with the size of passport photographs.
• Evidences of the ability to meet the medical costs: Banks statements or a sponsorship letter.
• Proof of Residence: National ID, utility bills, or similar documents.

Step 3: Apply for the Medical Visa

• This can be done by going directly to the official website of the Indian embassy or the Indian consulate in the country of your residence.
• The e-Medical Visa or Regular Medical Visa application form has to be completed.
• In case if the visa fee is applicable then the candidate will have to pay this fees online.
• Send the application with necessary documents to the nearest Indian consulate or the visa centre where such facilities are offered.

Step 4: Wait for Processing & Approval

• Delivery time is 3-7 working days and may vary depending on the country.
• If granted, the visa gets stamped on the passport to show that the holder is entitled to enter the country of destination.

Step 5: Travel to India & Report to the Hospital

• When going for medical purposes, clients should ensure to carry all their medical documents and a copy of their visa.
• Register with the local Foreigner Regional Registration Office (FRRO) if necessary within 14 days from the arrival in India.
• Continue with medical assessment of the hospital and its transplants.

Bone marrow Transplant Procedure in India

Before receiving a bone marrow transplant in India, there are a few things you should do. It is essential to complete these stages prior to beginning the transplant process itself.

• Pre-transplant Procedure: To ascertain the kind of bone marrow you need, you must first have a bone marrow test. To make sure you are a good candidate for the surgery, your doctor will do a complete evaluation of your medical history in addition to a physical examination. There are a few days left in this phase.
• Conditioning step: To either kill the cancer cells or suppress the immune system, you will receive a dose of radiation, chemotherapy, or both during this step. By taking this procedure, the bone marrow will be prepared to receive the freshly transplanted healthy stem cells.
• Bone marrow transplantation: In the upper chest, a central venous catheter is inserted. This allows the body to receive an injection of a healthy stem cell. The tube allows the fluid that contains healthy stem cells to enter the heart directly.

Following that, the body begins to multiply these healthy stem cells, eventually forming bone marrow. After that, the bone marrow starts to develop and make stem cells. It is usually not necessary to do surgery.

Recovery Process

The recovery process after a bone marrow transplant is a gradual process involving hospital stays, monitoring for infection and graft-versus-host disease, and rebuilding the immune system. Patients are at increased risk of infections during this time. Medications are needed to suppress the immune system and prevent GVHD. Maintaining a healthy diet is crucial for healing. Regular follow-up appointments are necessary to monitor progress, manage complications, and adjust medications.

What are the Factors Affecting Bone marrow transplants Cost?

The following are the factors that affect bone marrow replacement cost in India:

• Pre-Evaluation Cost - Multiple tests are performed before the transplant to understand the patient's vital statistics. These reports help the doctors use these statistics to determine if a patient is ready for surgery or not.
• Cost of Chemotherapy - Conditions like leukaemia may require the patient to undergo a few cycles of chemotherapy before receiving a bone marrow transplant. The expense of treating that particular condition as a whole increases due to the chemotherapy regimen.
• Type of Hospital - Additionally, bone marrow transplant expenses vary from hospital to hospital and from one city to another. Whether a person chooses a multispecialty hospital, clinic, or bone marrow transplant facility usually affects the overall bone marrow treatment cost. The price also differs across cities.
• Age of the Patients - Another element that affects the bone marrow transplant price is the patient's age. Patients younger than 20 or small kids typically incur higher costs. This is because they need more attention and testing, and their overall length of hospitalisation is longer.

Best hospitals for bone marrow transplant in India

For patients receiving this crucial therapy, the top bone marrow transplant facilities in India offer top-notch medical attention, cutting-edge equipment, and comprehensive services. Among the best hospitals in India for bone marrow transplantation, patients can anticipate a successful course of therapy from pre-transplant evaluations to post-transplant recuperation.

• Fortis Memorial Research Institute, Gurgaon
• Artemis Hospital, Gurgaon
• Medanta- The Medicity, Gurgaon
• Apollo Hospital, New Delhi

Best surgeons for Bone Marrow Transplant in India

• Dr. Rahul Bhargava
• Dr. Gaurav Dixit
• Dr. Ashok Kumar Vaid
• Dr. Gaurav Kharya
• Dr. Vikas Dua (Pediatric BMT Specialist)
• Dr. Satya Prakash Yadav (Pediatric BMT Specialist)

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Case Study of our Patients Treated for Bone Marrow Transplant in India

Bone Marrow Transplant Surgery for a Nigerian Patient at BLK Hospital

• Patient Name: Ms. Ojielo
• Age: 38 years old
• Gender: Female
• Country of Origin: Nigeria
• Doctor Name: Dr. Dharma Choudhary
• Hospital Name: BLK Hospital, Delhi
• Treatment: Bone Marrow Transplant

Ms. Ojielo, a 38-year Nigerian female recognized with Hodgkin Lymphoma. Her circumstance had significantly affected her quality of life, leading to severe fatigue and weakened immunity. After gaining knowledge of treatment alternatives online, she selected GetWellGo to facilitate her scientific journey to India.

Upon her arrival in India, GetWellGo’s worldwide patient services branch arranged for her airport switch, accommodation, and clinic appointments, ensuring she had an easy and comfortable revel in. Under the expert care of Dr. Dharma Choudhary, a leading bone marrow transplant professional, Ms. Ojielo underwent a successful transplant at BLK Hospital.
Post-surgery, she became cautiously monitored for any complications, receiving specialised care. Over the next few weeks, her situation advanced appreciably, and her body replied properly to the transplant.

Expressing her gratitude, Ms. Ojielo shared:

"My treatment at BLK Hospital changed into genuinely lifestyles-changing. From the medical doctors to the medical coordinators, everyone ensured I felt secure and well taken care of throughout the method. I am thankful to GetWellGo for directing me through this journey and giving me a brand new life."

We celebrate Ms. Ojielo’s recuperation and wish her good health and happiness in the future.

Bone Marrow Transplant Surgery for a Kenyan Patient at BLK Hospital

• Patient Name: Mr. Erastus Mutahi
• Age: 50 years old
• Gender: Male
• Country of Origin: Kenya
• Doctor Name: Dr. Dharma Choudhary
• Hospital Name: BLK Hospital, Delhi
• Treatment: Bone Marrow Transplant

Mr. Erastus Mutahi, a 50-yr Kenyan guy diagnosed with Multiple Myeloma, a situation that seriously impacted his everyday lifestyles and ordinary well-being. As his health persisted to become worse, he began trying to find the high-quality remedy options. After enormous studies, he chose GetWellGo to facilitate his scientific journey to India.

Upon arrival in India, the global patient services department at GetWellGo ensured his smooth transition via arranging airport pickup, lodging, and appointments. With the expert care of Dr. Dharma Choudhary, a bone marrow transplant expert at BLK Hospital, Mr. Mutahi underwent a successful transplant.

Post-surgical treatment, he became carefully monitored for any headaches, receiving customized operative care. Over the next few weeks, his situation showed splendid development, and his body answered properly to the remedy.

Expressing his gratitude, Mr. Mutahi shared:

"My experience at BLK Hospital changed into lifestyle changing. From the medical doctors to the coordinators, all people ensured I felt good and well sorted at some point of the treatment. Choosing GetWellGo was the first-rate decision I made for my health, and I am particularly thankful for this second life."

We celebrate Mr. Erastus Mutahi’s healing and want him persevered proper health and happiness in his life.

Bone Marrow Transplant Surgery for an Iraqi Patient at BLK Hospital

• Patient Name: Mr. Mustafa
• Age: 27 years old
• Gender: Male
• Country of Origin: Iraq
• Doctor Name: Dr. Dharma Choudhary
• Hospital Name: BLK Hospital, Delhi
• Treatment: Bone Marrow Transplant

This is a real life experience of Mr. Mustafa, a 27-yr-old Iraqi man recognized with Leukemia, a lifestyle threatening condition that drastically impacted his health and day by day sports. As his condition worsened, he started searching for the great possible treatment alternatives and, after thorough research, selected GetWellGo to manual him via the medical system in India.

Upon arriving in India, the worldwide patient offerings branch at GetWellGo ensured his journey changed into smooth with the aid of arranging airport transfers, appropriate lodging, and medical institution appointments. Under the expert care of Dr. Dharma Choudhary, an exceedingly professional bone marrow transplant expert at BLK Hospital, Mr. Mustafa efficiently underwent a bone marrow transplant.

Following the surgery, he was intently monitored for any headaches, receiving intensive operative care. Over the next few weeks, his situation improved notably, and his body replied properly to the remedy, marking a brand new beginning in his life.

Expressing his gratitude, Mr. Mustafa shared:

"My treatment at BLK Hospital was great. From the instant I arrived, I felt nicely cared for. The doctors, clinical staff, and coordinators made certain that I felt good at some point of the whole treatment. Choosing GetWellGo became the nice selection for my remedy, and I am all thankful for this second chance at my life."

We celebrate Mr. Mustafa’s successful restoration and desire him persisted health and happiness within the future.
 

FAQ

1. How can I apply for, obtain, or schedule a bone marrow transplant appointment in India?

• We can assist you in finding the top bone marrow transplant hospital in India. Check us out at getwellgo.com, our official website. To schedule a bone marrow transplant appointment in India, fill out the form below and include all of your information. We present the top hospitals and medical professionals for bone marrow transplant treatments based on the input.

2. What dietary recommendations should I follow after BMT?
Here are some suggestions for managing wellbeing and keeping a healthy diet:

• Always keep your body hydrated.

• Refrain from consuming alcohol.

• Consume whole-grain cereal, and fruits; cut back on salt.

• Increase the amount of fiber and green veggies in your diet.

• Eat extra lean meats to get your protein needs met.

3. Why should I prefer India for bone marrow transplant?

• The Indian healthcare system is equipped with highly skilled physicians and teams for both surgical and post-operative care who can manage complicated cases at an affordable price.  Medical procedures and treatments in India cost almost half as much as in the West and other wealthy nations.