Glioblastoma Cancer Treatment in India for International Patients

Discover advanced glioblastoma cancer treatment in India for international patients, with expert neuro-oncologists, cutting-edge therapies, and affordable care options.

Glioblastoma Cancer Treatment in India for International Patients

  • Category

    Cancer

  • Published By

    GetWellGo Team

  • Updated on

    28-Jul-2025

Glioblastoma cancer treatment in India

Combination of ultrasensitive tests, surgery, radiotherapy, and chemotherapy is performed in one of the leading multispecialty hospitals during Glioblastoma Cancer Treatment in India. Glioblastoma being a Grade IV astrocytoma is classified as one of the most aggressive and difficult brain cancer, yet, in India, equal quality treatment is available at a much cheaper price than as is available in many western nations.

Treatment options of Glioblastoma:

Surgical Resection (Craniotomy)

  • Objective: Maximal non-hazardous excision of the tumor.
  • Methods: Image-guided neurosurgery, awake brain surgery (in the case of brain tumors that are close to eloquent regions), neuro-navigation systems.

Radiation Therapy

Techniques used:

  • IMRT (Intensity Modulated Radiation Therapy)
  • IGRT (Image-Guided Radiation Therapy)
  • SRS (Stereotactic Radiosurgery)
  • Proton Therapy (Many centers offer this)

Chemotherapy

  • The commonest oral chemotherapy is temozolomide (TMZ).
  • Given together with radiotherapy, but also as maintenances cycles.

Tumor-Treating Fields (TTF)

  • A newer non-invasive option that is available at a couple of centers in India.

Targeted Therapy and Immunotherapy (in rare instances)

  • MGMT, IDH mutation and EGFR amplification molecular markers.

Palliative Care

  • In this more advanced stage, attention is paid to quality of life and symptom control.

Best hospitals for glioblastoma in India

Glioblastoma Multiforme Treatment India

The most lethal kind of primary brain tumor (WHO Grade IV) is Glioblastoma Multiforme (GBM). Treatment in India is conducted according to world standards that include advanced surgery, focused radiotherapy, Chemotherapy and other new developments at internationally recognized hospitals with a huge saving in cost.

Indian Standard Protocol of Treatment of GBM

Diagnosis & Evaluation

  • Contrast-MRI brain
  • MR spectroscopy / FMRI
  • Surgical Resection or Biopsy
  • Molecular markers: IDH mutation, MGMT promoter methylation, EGFR amplification
  • PET-CT (in some instances to evaluate the spread of tumor)

Neurosurgery in Urology

  • The objective: Maximal safe excision

Techniques used:

  • Image-guided craniotomy (neuronavigation)
  • Intraoperative MRI
  • Awake surgery (in the event the tumor is close to language or motor regions)
  • Neuro-monitoring

Radiation Therapy

  • Begins 3-6 weeks after the surgery.
  • Conventional regimen 60 Gy in 30 Fractions in 6 weeks

Advanced techniques:

  • Intensity-Modulated Radiotherapy (IMRT)
  • Image-Guided Radiotherapy - IGRT
  • SRS (Stereotactic Radiosurgery) of residual/recurrent GBM
  • Proton Beam Therapy 

Chemotherapy

  • Temozolomide (TMZ): In combination with radiation and then further continued in 6-12 cycles during one month.
  • In some cases, new agents can be used such as Bevacizumab (anti-VEGF).

Upcoming/Assisting Treatments

  • Tumor-Treating fields (TTF) (listed in a few Indian centers)
  • Genetically-based targeted therapy
  • Clinical trials (several centers also engage in trials of GBM).
  • Neurophysiotherapy, speech therapy (neurorehabilitation, palliative care)

Factors Affecting Cost of Glioblastoma Treatment in India

Glioblastoma management in India is a multi-stage process comprising surgery, radiotherapy, chemotherapy, diagnostics, and follow-up. The overall expense can differ considerably based on a variety of clinical, technological, and logistical reasons.

  • Extent of Surgery Required
  • Hospital & Location
  • Radiation Therapy Type
  • Chemotherapy Regimen
  • Molecular & Genetic Testing
  • Duration of Hospital Stay & Room Type
  • Post-operative & Supportive Care
  • Follow-up Scans & Medications
  • International Patient Services
  • Complications or Recurrence

Top Neurosurgeons for Glioblastoma in India

Glioblastoma brain tumor surgery in India

The first and most important intervention in the management of this aggressive brain cancer is the surgery of glioblastoma Multiforme (GBM). India is considered the global destination of advanced neurosurgery at a lower cost, which has trained neurosurgeons, top-notch technology, and hospitals with JCI/NABH accreditation.

Goal of GBM Surgery

  • Maximal Safe Resection: Try to take out as much tumor as you can but to leave intact important functions of the brain.
  • They can often not be completely removed as they infiltrate the healthy tissue, but tumor shrinkage increases survival and the success of the radiation and the chemotherapy.

Surgical Methods

Conventional Craniotomy

  • Alternative surgery against removing the tumor by standard open brain surgery.

Image-Guided Surgery (Neuronavigation)

  • Takes MRI/CT caliper measurements to find and eliminate precise tumor location.

Activated Brain Surgery

  • It is conducted when the tumors are in proximity with the speech or motor areas to track reaction in real-time in the patient.

Intraoperative MRI/ CT

  • Guarantees the highest amount of tumor when conducting surgery.

Neuro-Monitoring

  • Monitors the activity of the brain to prevent damage during removal.

Performance of Endoscopic Surgery (where possible)

  • Less invasive method, mostly in deep seated or midline tumor.

Advanced glioblastoma therapy in India

Glioblastoma Multiforme (GBM) is a type of brain tumor that is quite aggressive and resistant to treatment. Nonetheless, a variety of advanced, globally-compatible therapies, which includes surgery, accurate radiotherapy, chemotherapy and other new kinds of treatment, are provided at low and reasonable prices in India.

India has access to advanced therapies of Glioblastomas:

Neuronavigation-Assisted Surgery

  • Objective: Resection of the maximum safe tumor

Tools Used:

  • Navigation systems having MRI/CT-integration
  • When a tumor involves the speech/motor cortex, awake craniotomy is done.
  • Intraoperative Magnetic Resonance (iMRI)
  • Shrinks the leftover tumor and improves survival

High-tech radiation treatment 

  • Adjunctive use administered 3-6 weeks post-surgery.
  • IMRT: Preserves normal tissue, conforms to shape of tumor    
  • IGRT: Image guided real-time in radiation    
  • SRS (e.g., Gamma Knife, CyberKnife): Accurate, high dose radiotherapy of the small remaining/recurrent GBM    
  • Proton Therapy: No excessive damage to healthy tissues; most accurate with pediatrics and complex treatments    

Chemotherapy + Targeted Therapies

  • Temozolomide (TMZ) is the gold standard oral chemotherapy.
  • Bevacizumab (Avastin) - recurrence anti-angiogenic agent.
  • Lomustine (CCNU) - reoccurring/ resistant tumour.
  • Testing of MGMT methylation decides the effectiveness of TMZ.

Tumor Treating Fields (TTF) - (Narrow Availability)

  • Wearable technological device, applied non-invasively, which causes electric fields targeting to disrupt tumor cell division.
  • Still in the fledgling stage in India and can be found in few research-based individual hospitals.
  • In many cases co-administered together with chemotherapy.

Molecular and genetic profiling

Assists in individualizing treatment with the help of indicators that include:

  • IDH mutation
  • Methylation of MGMT promoter
  • co-deletion 1p/19q    
  • EGFR amplification
  • Other hospitals liaise with international labs to do a detailed report.

Clinical Trials & Immunotherapy (Limited Access)

  • ICIs- immune checkpoint inhibitors
  • CAR-T cell therapy (in GBM only early-stage)
  • Experimental therapies Vaccine-based

Affordable glioblastoma treatment in India with GetWellGo

GetWellGo is a reliable Indian medical tourism facilitator that connects overseas patients with leading hospitals and cost-effective treatment for complicated conditions such as Glioblastoma Multiforme (GBM). It assists patients in coordinating every step of their journey — from diagnosis to post-treatment follow-up — in an efficient, transparent, and caring manner.

Why Choose GetWellGo for Glioblastoma Treatment?

GetWellGo is regarded as a leading supplier of healthcare services. We help our foreign clients choose the best treatment locations that suit their needs both financially and medically.

We offer:

  • Complete transparency
  • Fair costs.
  • 24 hour availability.
  • Medical E-visas
  • Online consultation from recognized Indian experts.
  • Assistance in selecting India's top hospitals for Glioblastoma treatment.
  • Expert neurosurgeon with a strong track record of success
  • Assistance during and after the course of treatment.
  • Language Support
  • Travel and Accommodation Services
  • Case manager assigned to every patient to provide seamless support in and out of the hospital like appointment booking
  • Local SIM Cards
  • Currency Exchange
  • Arranging Patient’s local food
     

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