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Indications: It is used to cure cancerous tumors or cancerous tissues.
When it is used: This procedure is done when the cancer is well-defined, that is, it has not spread much.
Examples: Mastectomy for breast cancer, tumor removal for brain cancer.
Radiation Therapy
Function: To irradiate and thereby kill cancerous cells prevalent in a patient’s body.
Radiation Therapy Types
External Beam Radiation (from outside the body)
Endocavitary Radiation / Internal Radiation (radiation given within the body usually through seeds)
Where it is applied: Precisely before a surgery operation to reduce the size of tumors, immediately after a surgery to destroy any cells left behind, and in perfection only.
Chemotherapy
Anticancer drugs work with the purpose of destroying the rapidly dividing malignant cells.
When used: In cancer that extend to other organs or are innately malignant.
Some of the side effects include hair loss, fatigue as well as nausea because it has an impact on healthy cells that divide rapidly.
Immunotherapy
To gain this objective, one has to enhance its immune system so as to overcome this cancer ailment.
Immunotherapy Types:
Immune Checkpoint Inhibitors (release the restraints on the immune system)
A method of auto-immunotherapy through genetically modified T-cells that targets cancer cells.
When used: Especially for cancers like melanoma, lung cancer, some blood cancers.
Targeted Therapy
Goal: Target and neutralize particular proteins that assist in cancer development.
Examples:
HER2-targeted drugs for breast cancer.
EGFR inhibitors for lung cancer.
Advantages: Generally, it is less associated with side effects as compared to Chemotherapy.
Hormone Therapy
Used to block hormones that feed some forms of cancers such as the breast or prostate cancer.
When used: In hormone-sensitive cancers.
Examples: Tamoxifen for breast cancer.
Stem Cell (Bone Marrow) Transplant
Purpose: The aim is to transplant healthy stem cells thus replacing the damaged/bad bone marrow cells.
When used: Blood cancers like leukemia, lymphoma, myeloma.
Precision Medicine (Personalized Therapy)
For instance, if the clients have specific genetic makeup or tumor markers that are susceptible to therapy, then the treatments to be administrated have to correlate with such characteristics.
Trend: There is a trend of increase especially among uncommon cancer types.
Palliative Care
Rationale: This is because the common management aim is to help a patient to minimise their symptoms, while enhancing their quality of life.
In what cases: when curing a disease isn’t possible or when it is used in combination with curative treatment.
Bone Cancer Treatment Options
Surgery
Main treatment for most bone cancers.
Goal: Remove the tumor completely.
Types:
Surgical treatment: This is where a doctor amputates the tumor together with the affected limb but preserves the limb by replacing the bone with a metal one or a bone graft.
Surgery: Since ample development has already forced this as a plan B in numerous cases, today it is very rare, but can be carried out if cancer has metastasized to the extent that it is impossible to remove it from the limb.
They may require a rehab that will give them physical therapy so that they regain their former health.
Chemotherapy
Purpose: Eradicate cancer cells that are difficult to be operated on.
When used: Especially for aggressive types like osteosarcoma and Ewing sarcoma.
Use: Before surgery for shrinking the size of the tumor and after the surgery for eliminating the remaining cells if any.
Some 5 common chemotherapeutic agents are Doxorubicin, cisplatin, methotrexate, ifosfamide.
Radiation Therapy
Functions: To eradicate cancer cells using powerful rays.
When used:
In cancers that can only be partly resected.
It is valid in the case of Ewing sarcoma which is sensitive to radiation than to chemotherapy.
Type: External beam radiation.
Targeted Therapy
Goal: In this way, block certain proteins that aid the cancer cells to develop.
Example:
Its use is also helpful in certain situations with the giant cell bone tumors.
Treatment and prognosis is still under investigation for other forms of bone cancers.
Immunotherapy
For bone cancers, it is still in its experimental stage, yet there is more ongoing research.
There is the possibility of making clinical trials, especially if it is a difficult case.
Cryosurgery (Freezing Treatment)
Aim: To eliminate the cancer cells by freezing them.
Inflammation is: Sometimes used instead of open surgery for small tumors that are easily deformed.
Palliative Treatment
If the cancer is advanced, the purpose must be to minimize and treat symptoms such as pain.
May include:
Pain management
Radiation to control tumor size
Supportive care
Treatment Options Stage 4 Cancer
Stage 4 cancer indicates that cancer has affected other tissues or organs of the body, apart from the origin organ. That is why the treatment goals tend to change to the following objectives. To arrest the cancer means to slow down the acceleration or put a check on the further development of the disease.
Relieving symptoms
Extending life
Ensuring a proper quality of life as much as can be expected
Cancer stage 4 treatment varies depending on the type of cancer for example lung, breast, colon cancer among others, location of cancer and the client’s condition hence treatment that oncologist usually consider will be as follows:
Systemic therapy
Chemotherapy
Drugs that kill fast-growing cancer cells everywhere in the body.
Often the main treatment for stage 4 cancers.
Targeted Therapy
Antimetabolites blocking some of the mutations or proteins that enable the cancer to proliferate.
Normally used drugs specifically for breast cancer targets include the HER2-targeted drugs while for lung cancer; the EGFR inhibitors.
Immunotherapy
A positive way through which it impacts on the body is that it strengthens the body immunity to fight cancer.
Works well in cancers like melanoma, lung cancer, kidney cancer, some head & neck cancers.
Hormone Therapy
For the diseases such as breast or prostate cancer that are hormone sensitive.
Interferes with the release of the hormones that help stimulate cancer growth.
Radiation Therapy (local control)
Uses: Tumor reduction, pain control, and cessation of hemorrhage.
Applied when: There are certain regions (such as a tumor that may compress the nerves or organs).
Surgery
Purpose: Diplomatic ablation of a growth which produce signs of a disease such as haemorrhage or obstruction.
Used selectively: For instance when a single brain or liver metastasis is being treated if it relieves the patient’s pain.
Palliative Care (Supportive Care)
Goal: Relieve symptoms like pain, breathlessness, fatigue, nausea.
It is, therefore, important to note that the use of palliative care also does not equal giving up; the care is administered alongside the treatment.
Clinical Trials
Chances of entering trials: Some patients are eligible for experiments that involve using radical treatments.
Why: They might be beneficial when the usual treatments fail to work and provide other alternatives.
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