Where Is Bone Marrow Located? A Complete Guide for Nigerian Patients
Bone marrow is soft spongy tissue inside certain bones. Unlike the same name, it is not found in the muscles or directly in the spinal cord. The bones have a hard outer structure to protect bone marrow.
After being diagnosed with sickle cell disease, leukemia, lymphoma or other blood disorders, many people wonder, where is bone marrow located? The bone marrow plays a vital role in the human body for making blood cells that carry oxygen, help fight infection and prevent bleeding. Nigerian patients who are considering advanced treatment in India might want to check out the place and function of bone marrow in order to gain insight into the reason why some blood disorders necessitate specialized therapy such as a bone marrow transplant. This guide tells you about the function of bone marrow and red marrow versus yellow marrow; where is it located; and when might a patient need a bone marrow transplant?
Where is Bone Marrow found in the Human Body?
Bone marrow is soft spongy tissue inside certain bones. Unlike the same name, it is not found in the muscles or directly in the spinal cord. The bones have a hard outer structure to protect bone marrow. When people ask, where bone marrow is located, you can get different answers depending on the age of the person who's asking. In children, blood-forming bone marrow exists in numerous bones of the body. In adults the marrow of certain bones is responsible for most production of blood cells.
The significant places are:
Bones of hip bones or pelvic bones
Breastbone (sternum)
Ribs
The backbone
Skull bones
Shoulder blades
The ends of some long bones, such as femur, humerus
The pelvic bones are especially significant as they have a lot of active bone marrow. This is why doctors often take a bone marrow biopsy from the back of the hip bone.
What is Bone Marrow?
Bone marrow is a soft tissue inside the hollow parts of bones. It has stem cells which develop into other blood cell types.
These include:
Red blood cells – Transport oxygen around the body.
White blood cells – protect against infections.
Platelets – promote blood clotting and prevent bleeding.
The bone marrow makes millions of new blood cells every day. This process is fundamental for good health. If there are problems with the bone marrow, the body may not make enough healthy blood cells. This can cause anemia, recurrent infections, bleeding disorders or other health issues.
Types of Bone Marrow
The bone marrow can be of two kinds, red marrow and yellow marrow.
Red Bone Marrow
Blood cells are formed by red marrow. It has hematopoietic stem cells that can give rise to red blood cells, white blood cells and platelets.
Red marrow is present in adults primarily in the ends of certain long bones and the flat bones.
Yellow Bone Marrow
Yellow marrow is rich in fat cells and is a source of energy. It is more common in the marrow within the long bones of adults.
In some emergency situations, yellow marrow can transform back to red marrow to produce more blood cells.
Importance of Bone Marrow for Nigerians with Blood Disorders
Bone marrow is the central hub of many diseases in Nigerian population including inherited and acquired blood diseases.
Some common conditions include:
Sickle cell disease
Leukemia
Lymphoma
Aplastic anemia
Myelodysplastic syndromes
Multiple myeloma
Some immune system diseases
SCD is a condition in which the red blood cells are abnormal due to a genetic defect in the hemoglobin. Leukemia is a type of cancer that develops in the white blood cells formed in the bone marrow. Bone marrow diseases can affect the body since it is the source of blood cells.
What are ways that doctors examine bone marrow?
Blood counts may be abnormal or a patient may have symptoms that suggest a blood disorder in which case doctors may order bone marrow tests.
Bone Marrow Aspiration
A small amount of bone marrow is extracted from the body and sent to a laboratory for testing using a needle.
Bone Marrow Biopsy
Small pieces of solid bone marrow are taken, typically from the back of the hip bone. These procedures allow doctors to look at how many, how big and how developed the blood-forming cells are.
Bone marrow tests might be ordered for diagnosis of:
Leukemia
Unexplained anemia
Low platelet counts
Bone marrow failure
Certain cancers
Disorders of blood cell formation.
What is Bone Marrow Transplant?
Bone marrow transplant (also known as a hematopoietic stem cell transplant) is the replacement of damaged or unhealthy blood-forming stem cells with healthy stem cells. Treatment is considered for people who no longer have healthy blood cells in their bone marrow.
A bone marrow transplant might be recommended for diseases like:
Leukemia
Lymphoma
Multiple myeloma
Severe aplastic anemia
Sickle cell disease
Some congenital immune diseases
The purpose of the treatment is to get a person's blood cell production back to normal and to improve his or her general health.
How Bone Marrow Transplant Work?
There are several significant steps that are usually involved in a bone marrow transplant.
Medical Evaluation
The patient's diagnosis, medical history, blood tests, organ function and overall fitness are discussed with the doctor.
Donor Matching
In total, an allogeneic transplant, doctors look for a donor with an appropriate human leukocyte antigen (HLA) match.
A sibling could be a possible donor, however other donors or alternative donors could be considered.
Conditioning Treatment
Patient is given chemotherapy and sometimes radiation therapy prior to the transplant.
This helps to ready the body by decreasing the number of bone marrow cells that are diseased and by dampening the immune system.
Stem Cell Infusion
The healthy stem cells are then dripped into the patient's bloodstream via an IV. The cells migrate to the bone marrow where they start to make new blood cells.
Recovery and Monitoring
Patients should be monitored very closely for infections, GvHD, blood counts and other complications.
Is Bone Marrow Transplant Available for Nigerian Patients in India?
Yes. There are several advanced hematology and bone marrow transplant hospitals and transplant centers in India that cater to international patients.
Patients suffering from blood disorders in Nigeria can seek specialist care in India for blood disorders and travel to India for treatment.
India has access to experienced hematologists, transplant physicians, diagnostic laboratories and supportive care team. Treatment depends on patient's medical condition, donor availability, age and general health.
Advanced hematology and transplant services are available in major cities in India.
GetWellGo facilitates appointment setting, consultation, hospital estimates, flights, accommodation and after-treatment support for all patients traveling abroad to India.
Bone marrow transplant cost for Nigerian patients in India
There are several factors that will affect the cost of a bone marrow transplant in India.
Patients should consult a reputable hospital or transplant specialist to get an estimate of their treatment after providing their medical records. Before traveling to Indian hospitals, GetWellGo can help Nigerian patients with medical opinions and cost estimates.
The recovery after bone marrow transplant
Post-transplant recovery varies from person to person who has undergone a bone marrow transplant. Patients may need to have their immune system rebuilt and regular monitoring of their medical status is necessary.
In Recovery the doctors may recommend:
Regular blood tests
Infection prevention measures
Prescribed medications
Nutritional support
Keeping away from dense areas at high risk times
Scheduled follow-up consultations
The role of the family and caregiver also is significant in the patient's recovery. Continued communication with the transplant team in India may be required along with local healthcare providers for patients who are travelling from Nigeria.
Conclusion
Knowing the location of bone marrow can help patients and families understand the place of production of blood cells and the role of bone marrow disorders in affecting the whole body. Bone marrow is found mainly within the bones including the pelvis, ribs, sternum, vertebrae and more and is essential for maintaining health in the production of blood. If your doctor recommends, a bone marrow transplant can be an important treatment option for patients in Nigeria who have been diagnosed with serious blood disorders. GetWellGo helps Nigerian patients undergoing treatment in India to coordinate medical consultation, hospital selection, treatment planning, travel support and post-treatment coordination.
Bone Marrow Transplant GetWellGo
GetWellGo is regarded as a leading supplier of healthcare services. We help our Nigerian clients choose the best treatment locations that suit their needs both financially and medically.
We offer:
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Assistance during and after the course of treatment.
Medicines, blood transfusions, chemotherapy or bone marrow transplant may be recommended for more serious or advanced bone marrow diseases. The availability of advanced transplant facilities and experienced haematologists in India is another reason why ma
Bone marrow biopsy is an important diagnostic test that is performed to evaluate blood disorders and diseases when the cause of the blood disorder is unclear.
Sickle cell disease is a severe inherited blood condition which occurs in millions of people around the world especially in Africa. In Nigeria, there are many children and adults with sickle cell anaemia who have frequent pain attacks, severe anaemia, inf
A bone marrow transplant may be a life-saving treatment option for patients with severe blood diseases, cancer or inherited disorders like sickle cell disease in Nigeria.
Knowledge of the condition can help the patient and family recognize early signs and symptoms and seek and receive proper medical treatment as well as make informed choices.
Sickle cell is a blood disease passed on in the family which causes abnormally shaped red blood cells. Some red blood cells turn into sickle-shaped cells that cannot bend and flex like normal RBCs and pass through the small blood vessels.